PureDyne - Creative Media Linux

If you're an artist working with digital content you might want to give this PureDyne Linux Distro a try.

Based on Ubuntu and Debian Live and available as a "Live OS" you can simply boot off CD/DVD/USB, this
Puredyne is tuned for realtime audio and video processing, with a low latency kernel and offering the high responsiveness needed by artists working in this field.

Inside you'll have all you might need:

• audio
  puredata, supercollider, csound, chuck, ladspa plugins, ardour, audacity, ecasound, ...
• graphics
  gimp, inkscape, fluxus, freej, processing + extras, imagemagick, gthumb, gphoto2, ...
• multimedia
  mplayer, vlc, avidemux, kino, mencoder, transcode, luvcview, xawtv, recordmydesktop, ...
• streaming
  icecast2, ices2, ffmpeg2theora, oggfwd, darkice, darksnow, gstreamer, dvswitch, ...
• network
  firefox, links2, network-manager, wireless-tools, ssh, telnet, gftp, irssi, nfs, ...
• devel
  gcc, make, patchutils, subversion, mercurial, bzr, emacs-goodies-el, java jdk, python, ...

Definitely worth a shot:

Ubuntu Studio

If you're into Multimedia and worry about leaving Windows operating systems - even though you'd really like to try out that "Ubuntu" buzz and see if you can manage with it - then you should really give UbuntuStudio a try.

Ubuntu Studio, as they say:

Ubuntu Studio is aimed at the GNU/Linux audio, video and graphic enthusiast as well as professional.

We provide a suite of the best open-source applications available for multimedia creation. Completely free to use, modify and redistribute. Your only limitation is your imagination.

It includes, among others:

Audio

• Ardour 2 - A multitrack recorder/editor

Image

• GIMP
• Inkscape
• Blender
• RAW camera files tools
• Wacom drawing tablets support

Video

• PiTiVi
• Kino
• Cinepaint

Those might be all the multimedia tools you'll ever need.

(or you can give Studio64 a try as well)